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Crysvita Injection Therapy

Discover why thousands of patients choose Haven Infusion as their preferred place to receive infusions and injections.

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What is Crysvita?

Crysvita (burosumab-tkrb) is an FDA-approved treatment to treat:

X-linked hypophosphatemia (XLH)

This is a rare genetic condition that causes low phosphate levels, leading to weak bones and growth issues in children, and bone and muscle pain in adults.

Crysvita helps your body hold on to more phosphate, which helps your bones grow and stay strong.

Crysvita is a biologic that is injected subcutaneously (under the skin).

How Often Do I Need Crysvita Injections?

Patients typically receive Crysvita infusions every 2-4 weeks depending on the patient.

Your first appointment usually takes about 1 hour, broken down approximately as follows:

Check-in & forms: ~10-15 min
Preparation: ~5–10 min
Medication administration: <5 min
Post-treatment monitoring: ~15-30 min

Further appointments can shorten to 30 minutes if you tolerate the medication well.

How Do I Prepare for My Crysvita Injection?

Here’s how you should prepare for your appointment:

Consult Your Healthcare Provider

Medical History Review: Ensure your healthcare provider has a complete and up-to-date medical history, including any allergies, current medications, and past reactions to other medications. Your doctor will have sent these records to Haven Infusion beforehand.
Pre-Appointment Testing: Complete any required blood tests or other pre-appointment tests as recommended by your healthcare provider.

Pre-Infusion Medications

Prescription Pre-Medications: You may require pre-medications to reduce the risk of a reaction or adverse event. Your referring provider will include any pre-medications when sending in your prescription order to Haven. Your Haven Infusion clinician will have these ready for you as part of your appointment.
Regular Medications: If you take other medications on a regular basis, be sure to consult with your doctor to see if you need to change how you take them while on Crysvita.

Hydration and Nutrition

Hydrate: Drink plenty of water in the days leading up to your injection to ensure you are well-hydrated. If you are a regular caffeine drinker, go lighter the morning of, since caffeine is dehydrating.
Eat Light: Have a light meal before your injection to help maintain your energy levels during the procedure.

Plan for Transportation

Arrange a Ride: Depending on the medication and your reaction to the injection, you might not feel well enough to drive yourself home. Consider arranging for someone to drive you or use a ride service.

By following these steps, you can help ensure that your injection is as safe and comfortable as possible. Always follow the specific instructions provided by your healthcare team.

Does Crysvita Have Any Side Effects?

Most patients tolerate Amvuttra well. If a patient does have side effects, the most common ones are headache, fever or redness/itching near the injection site.

If you have concerns about side effects, please feel free to discuss them with your doctor before starting treatment. As a specialist in infusion care, Haven Infusion operates with comprehensive and well-established safety protocols, and we are happy to share them with you.

How Much Does Crysvita Cost?

Coverage varies depending on your insurance plan. Our goal is to lower your out-of-pocket costs as much as possible. When your doctor sends us your information, we will verify your benefits and help you find assistance programs that you qualify for.

We always review your expected out-of-pocket costs with you before scheduling your first appointment to ensure full transparency. And, if you have any questions or need help understanding how your insurance works, feel free to ask.